Your daughter's journey is so similar to my daughter's. Your son, Jacob's journey, is so similar to my daughter's, minus murder.
You're right about people judging the parents for their child's behavior, when the parent is doing everything possible to bring about a positive result. I also went to therapy and counselors ad nauseam, with no result. I tried working with the school, tried to find clubs and groups that she would find engaging, hoping she would find a purpose that would bring her joy.
Nothing worked.
My heart goes out to you. I feel your pain.